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METHOD OF EXPRESSING GENE IN TRANSGENIC BIRD USING RETROVIRUS VECTOR AND TRANSGENIC BIRD THUS OBTAINED

机译:利用逆转录病毒载体和获得的转基因鸟在转基因鸟中表达基因的方法

摘要

PPROBLEM TO BE SOLVED: To provide a G0 transgenic chimera bird which produces an antibody. PSOLUTION: There are provided: a G0 transgenic chimera bird in which an antibody gene is introduced with a replication-defective retrovirus vector, and which produces an antibody by expressing the transgene; a production method for an antibody, which comprises recovering the antibody expressed by the produced G0 transgenic chimera bird; and a production method for a G0 transgenic chimera bird, which comprises incubating a bird fertilized egg and injecting a retrovirus vector into the fertilized egg excluding immediately after the initiation of the incubation. PCOPYRIGHT: (C)2011,JPO&INPIT
机译:

要解决的问题:提供一种产生抗体的G0转基因嵌合体鸟。

解决方案:提供一种G0转基因嵌合体鸟,其中将抗体基因与复制缺陷型逆转录病毒载体一起引入,并通过表达该转基因而产生抗体。一种抗体的生产方法,其包括回收由所生产的G0转基因嵌合鸟表达的抗体。 G0转基因嵌合鸟的生产方法,其包括将鸟的受精卵孵化,并在刚开始孵化后立即将逆转录病毒载体注射到受精的卵中。

版权:(C)2011,日本特许厅&INPIT

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