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Factor IX conjugates with extended half-life
Factor IX conjugates with extended half-life
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机译:IX缀合物具有延长的半衰期
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摘要
The present invention relates to conjugates of Factor IX that have been modified to include a biocompatible polymer moiety. The Factor IX conjugates are substantially free of contamination by Factor IXa. The Factor IX conjugates have improved pharmacokinetic properties, such as increased half-life, which results in dose sparing and less frequent administration.
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