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Reprogramming of cells by inducing pluripotency genes through the use of small molecule modulators

机译:通过使用小分子调节剂诱导多能性基因对细胞进行重编程

摘要

Method for reprogramming cells, compositions, and this invention relates to a kit. In one embodiment, the present invention contributes genes to become pluripotent or multipotent relates to a method comprising the step of inducing expression of at least one gene. In another embodiment, contribute genes to become pluripotent or multipotent, small molecule modulators that induce expression of gene 1, the method, the step of exposing the cells at least comprises. In another embodiment, the present invention can have the characteristics of ES cell-like, the enriched population of reprogrammed cells and reprogrammed cells can be differentiated or transformed re-differentiated into a variety of differentiated cell types further about. [Selection] Figure Figure 1
机译:重编程细胞,组合物的方法,本发明涉及试剂盒。在一个实施方案中,本发明贡献基因成为多能的或多能的,涉及一种方法,其包括诱导至少一个基因表达的步骤。在另一个实施方案中,贡献基因成为诱导基因1表达的多能或多能的小分子调节剂,该方法,暴露细胞的步骤至少包括。在另一个实施方案中,本发明可以具有类ES细胞的特征,富集的重编程细胞和重编程细胞可以被分化或转化,再进一步分化成多种分化的细胞类型。 [选择]图图1

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