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Multi-targeted RNAi therapeutics for scarless injury healing in the skin

机译:多目标RNAi治疗剂可在皮肤上实现无疤痕愈合

摘要

The present invention provides small interfering RNA (siRNA) molecules, compositions containing them, and methods of using them for improvement of skin scarless wound healing and other skin conditions, such as psoriasis and lupus-caused cutaneous lesions. The invention includes siRNA molecules and compositions containing them that inhibit the expression of one or more genes that promote pathological or undesired processes in wound healing and methods of using them.
机译:本发明提供了小的干扰RNA(siRNA)分子,包含它们的组合物以及使用它们来改善皮肤无疤痕伤口愈合和其他皮肤状况例如牛皮癣和狼疮引起的皮肤损伤的方法。本发明包括siRNA分子和包含它们的组合物及其使用方法,所述siRNA分子和包含它们的组合物抑制一种或多种基因的表达,所述一种或多种基因促进伤口愈合中的病理或不期望的过程。

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