Hybrids and a manufacturing method thereof with a basic polymer free base form drug and the layered-type silicate is added

摘要

This invention regards the pharmacy constitution and its production method of the mixed body where the water soluble base polymer is added to the mixed body substance of the base type medicine and the stratified type silicate of slightly soluble. As water soluble high-molecular, amino alkyl methacrylate copolymer (as for the proverb, yudorajitsuto E100 of the degusa corporation make (poly- (butyl methacrylate, (2 dimethyl amino ethyl) methacrylate and methyl methacrylate) the 1:2: 1) or poribiniruasetarujiechiruaminoaseteto (AEA) and the like you can use. Because of this, during brief raising the liquation ratio of the slightly soluble medicine with the presence machine mixed body substance which is used as the raw materials of the formulation oral up to 90%, although it improves the performance for internal absorptance it is effective.