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Lyophilized pharmaceutical composition with improved reconstitution time containing taxane derivative and process for its preparation
Lyophilized pharmaceutical composition with improved reconstitution time containing taxane derivative and process for its preparation
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机译:含有紫杉烷衍生物的具有改善的重构时间的冻干药物组合物及其制备方法
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摘要
The present invention relates to a lyophilized composition with an improved reconstitution time comprising a taxoid and a method thereof. More specifically, the present invention relates to a lyophilized composition with an improved reconstitution time prepared by mixing and dissolving a taxoid; cyclodextrin (CD); a hydrophilic polymer selected from the group consisting of hydroxypropylmethyl CeIIuIoSe (HPMC), polyethylene glycol (PEG), and polyvinylpyrrolidone (PVP); and a bulking agent of saccharides in water for injection; and lyophilizing the mixture, and a method thereof.
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