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H. pylori growth inhibitor containing α-N-acetylglucosaminyl-linked monosaccharide derivative

机译:含有α-N-乙酰氨基葡糖基连接的单糖衍生物的幽门螺杆菌生长抑制剂

摘要

The present invention herein provides a proliferation inhibitor of Helicobacter pylori comprising a compound that can simply be mass-produced, can specifically inhibit the proliferation of H. pylori, which has high safety and never generates any resistant bacteria, as well as a diet of a food or beverage, and a pharmaceutical preparation containing the proliferation inhibitor of Helicobacter pylori. The proliferation inhibitor of Helicobacter pylori comprises an alpha-N-acetyl-glucosaminyl bond-containing monosaccharide derivative represented by the following chemical formula (1) €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒGlcNAc1-alpha-O-Y€ƒ€ƒ€ƒ€ƒ€ƒ(1) (in the formula (1), Y is a straight-, branched- or cyclic- aliphatic hydrocarbon group having 1 to 27 carbon atoms or a straight-, branched- or cyclic- acyl group having 1 to 27 carbon atoms). The diet of the food, the beverage or the pharmaceutical preparation comprises the proliferation inhibitor of Helicobacter pylori.
机译:本发明在此提供了一种幽门螺杆菌的增殖抑制剂,其包含可以简单地大量生产,可以特异性地抑制幽门螺杆菌的增殖,安全性高,并且不会产生任何抗性细菌的化合物,以及一种饮食。食品或饮料,以及含有幽门螺杆菌增殖抑制剂的药物制剂。幽门螺杆菌的增殖抑制剂包含由以下化学式(1)表示的含α-N-乙酰基-氨基葡萄糖氨基键的单糖衍生物。(GlcNAc1-alpha-O-Y)(1)(式(1)中,Y为碳原子数为1〜27的直链,支链或环状的脂肪族烃基或碳原子数为1〜27的直链,支链或环状的酰基)。食物,饮料或药物制剂的饮食包含幽门螺杆菌的增殖抑制剂。

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