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Cat eye grass extract and its preparation manner and kuerusechin

机译:猫眼草提取物及其制备方法和苦参碱

摘要

The invention relates to the method of extracting active compounds from medicinal plant Euphorbia Lunulate Bge, consists of the following steps: The Acetone extractants of Euphorbia Lunulate Bge are abstracted and crude extracted by using organic solvents; the organic solvents extractants are subjected to inhibit production of NO activity test, and further isolate the extractants which have high production of NO inhibiting activity and no toxicity; then the isolated compositions are subjected to inhibit production of NO activity test again, and further refine the compositions which have high production of NO inhibiting activity; the achieved single compound is subjected to inhibit production of NO activity test and physical and chemical identification so as to definition its structure. The achieved compound has the activity of inhibiting production of NO, in which the structure of compound 1-3 are following formulas.
机译:本发明涉及一种从药用植物大戟大黄中提取活性成分的方法,包括以下步骤:提取大戟大黄中的丙酮萃取剂,并用有机溶剂进行粗提。对有机溶剂萃取剂进行NO活性抑制试验,进一步分离出具有高NO抑制活性且无毒的萃取剂。然后将分离出的组合物再次进行抑制NO活性产生的试验,进一步精制具有抑制NO高活性的组合物。对所获得的单一化合物进行NO活性测试和物理化学鉴定的抑制,从而确定其结构。所获得的化合物具有抑制NO产生的活性,其中化合物1-3的结构为下式。

著录项

  • 公开/公告号JP4686732B2

    专利类型

  • 公开/公告日2011-05-25

    原文格式PDF

  • 申请/专利权人 学校法人日本大学;王 立岩;

    申请/专利号JP20070501095

  • 发明设计人 王 立岩;北中 進;

    申请日2004-03-04

  • 分类号A61K36/18;A61K36;A61K31/7028;C07H17/07;A61P29;A61P19/02;A61P17/06;A61P43;

  • 国家 JP

  • 入库时间 2022-08-21 18:19:18

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