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Angiotensin I converting enzyme inhibitor wheat bran, barley bran, rice bran from

机译:血管紧张素I转化酶抑制剂小麦麸皮,大麦麸皮,米糠

摘要

PPROBLEM TO BE SOLVED: To economically and efficiently provide a polypeptide having activity for inhibiting angiotensin-I converting enzyme from wheat bran, barley bran and rice bran without adding protease or amylase, and further without adding a material harmful to the human body, and to provide a method for producing the polypeptide having hypotensive functions. PSOLUTION: The polypeptide having the activity for inhibiting the angiotensin-I converting enzyme is obtained by adding and mixing at least one kind of powder raw material selected from the group consisting of wheat flour at least containing the wheat bran, barley flour at least containing the barley bran and rice flour at least containing the rice bran, to and with water or a buffer solution, regulating the pH of the water or the buffer solution after the addition and mixing so as to be from 3.05 to 3.95, and reacting the product at 30-45°C for at least 4 hr or more. The method for producing the polypeptide having the hypotensive functions is also provided. PCOPYRIGHT: (C)2009,JPO&INPIT
机译:

要解决的问题:为了经济有效地提供一种具有抑制麦麸,大麦麸和米糠中的血管紧张素I转化酶活性的多肽,而无需添加蛋白酶或淀粉酶,并且无需添加对人体有害的物质,并提供生产具有降血压功能的多肽的方法。

解决方案:具有抑制血管紧张素-I转化酶活性的多肽是通过添加和混合至少一种选自至少包含小麦麸皮的小麦粉,大麦粉中的粉末原料而获得的。至少含有大麦麸和米粉的面粉,至少含有米糠的面粉,与水或缓冲溶液混合,并在添加和混合后将水或缓冲溶液的pH调节至3.05至3.95,并进行反应该产物在30-45℃下至少4个小时或更长时间。还提供了生产具有降血压功能的多肽的方法。

版权:(C)2009,日本特许厅&INPIT

著录项

  • 公开/公告号JP4686792B1

    专利类型

  • 公开/公告日2011-05-25

    原文格式PDF

  • 申请/专利号JP20100264688

  • 发明设计人 野方 洋一;

    申请日2010-11-29

  • 分类号C07K4/10;A61K38/55;A61P9/12;A61K36/899;A61K38/00;C12N9/99;C12P21/06;C07K1/12;C07K1/20;C07K1/14;C07K5/083;C07K5/062;C07K5/065;

  • 国家 JP

  • 入库时间 2022-08-21 18:19:15

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