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Antibacterial amino acid sequence derived from alpha-melanocyte-stimulating hormone
Antibacterial amino acid sequence derived from alpha-melanocyte-stimulating hormone
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机译:源自α-黑素细胞刺激激素的抗菌氨基酸序列
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摘要
The present invention is directed to a system for treating uro-genital conditions. One aspect of this invention involves the treatment system comprising one or more polypeptides with an amino acid sequence including KPV (SEQ ID NO: 1), MEHFRWG (SEQ ID NO: 2), HFRWGKPV (SEQ ID NO: 3), SYSMEHFRWGKPV (SEQ ID NO: 4), for treatment of uro-genital conditions. The one or more polypeptides can also be a dimer formed from any of the amino acid sequences above. Uro-genital conditions can include infections, inflammation or both. In one preferred embodiment of the invention, the uro-genital condition includes infection and/or inflammation of the vagina, vulva, urinary tract, penis, and/or the rectum. In another preferred embodiment of the invention, the one or more polypeptides are dissolved in a carrier. In another preferred embodiment of the invention, the one or more polypeptides are associated with a tampon for preventing toxic shock syndrome. In another preferred embodiment, the one or more polypeptides are associated with a contraceptive for prevention of sexually transmitted diseases or infections. In another preferred embodiment, the one or more polypeptides are associated with a suppository for insertion into the vagina or rectum. IMAGE
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机译:本发明涉及用于治疗泌尿生殖器疾病的系统。本发明的一个方面涉及一种治疗系统,其包含一种或多种具有氨基酸序列的多肽,所述多肽包括KPV(SEQ ID NO:1),MEHFRWG(SEQ ID NO:2),HFRWGKPV(SEQ ID NO:3),SYSMEHFRWGKPV(SEQ编号:4),用于治疗泌尿生殖器疾病。一个或多个多肽也可以是由以上任何氨基酸序列形成的二聚体。泌尿生殖器疾病可以包括感染,炎症或两者兼有。在本发明的一个优选实施例中,尿生殖器疾病包括阴道,外阴,泌尿道,阴茎和/或直肠的感染和/或炎症。在本发明的另一个优选实施方案中,一种或多种多肽溶解在载体中。在本发明的另一个优选的实施方案中,一种或多种多肽与用于预防毒性休克综合症的棉塞相关。在另一个优选的实施方案中,所述一种或多种多肽与避孕药有关,以防止性传播疾病或感染。在另一个优选的实施方案中,所述一种或多种多肽与用于插入阴道或直肠的栓剂结合。 <图像>
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