Being one assaying which measures the immunogenicity of the test

摘要

Provides assays for determining the immunogenicity of the vaccine, the vaccine epitope with a conformation associated with the immunogenicity active form of the vaccine, the present invention, immunogenicity and inactive form of the vaccine here a first ligand capable of binding to an epitope in the conformation associated with the immunogenicity active form of the vaccine, a sample of the vaccine, the method, the immunogen of the vaccine here also contains a fragment having a conformation associated It comprises measuring the amount of a second ligand that binds to the vaccine sample and the amount of the first ligand is exposed and a second ligand capable of binding to the fragment in the conformation associated with the inactive form, bound to the vaccine sample .