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COMPOSITION FOR USE AS A PEPTIDE RETENTION STANDARD AND A METHOD OF PREDICTING PEPTIDE HYDROPHOBICITY IN LIQUID CHROMATOGRAPHY
COMPOSITION FOR USE AS A PEPTIDE RETENTION STANDARD AND A METHOD OF PREDICTING PEPTIDE HYDROPHOBICITY IN LIQUID CHROMATOGRAPHY
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机译:用作肽保留标准的组合物和预测液相色谱中肽疏水性的方法
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摘要
A composition comprising synthetic peptides for use as a peptide retention standard in liquid chromatography applications is disclosed Said synthetic peptides have a broad range of hydrophobicity while maintaining low variation in their molecular weights The synthetic peptides disclosed consist of the ammo acid sequences LGGGGGGDGSR, LGGGGGGDFR, LLGGGGDFG, LLLGGDFR, LLLLDFR, LLLLLDFR A method of predicting the hydrophobicity of an unknown peptide in liquid chromatography using a composition of peptide retention standards and a method of developing a Universal Hydrophobicity Index (UHI) for the measurement of peptide hydrophobicity in liquid chromatography are also described
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