首页>
外国专利>
TREATMENT OF ALCOHOL ABUSE AND ALCOHOLISM USING MODULATORS OF NEUROSTEROID BINDING SITES ON GABAA RECEPTORS
TREATMENT OF ALCOHOL ABUSE AND ALCOHOLISM USING MODULATORS OF NEUROSTEROID BINDING SITES ON GABAA RECEPTORS
展开▼
机译:在GABAA受体上使用神经甾类结合位点调节剂治疗酒精滥用和酒精中毒
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides methods for reducing alcohol drinking behavior in humans and treating acute alcohol poisoning through the use of neutral or negative modulating agents of the neurosteroid sites on GABAA receptors. These agents avoid the unwanted side-effects of opiate antagonists and displays specificity toward the neurosteroid binding sites on GABAA receptors.
展开▼
机译:本发明提供了通过使用GABA A Sub>受体上神经甾体位点的中性或负性调节剂来减少人类饮酒行为和治疗急性酒精中毒的方法。这些药物避免了阿片拮抗剂的不良副作用,并且对GABA A Sub>受体上的神经甾体结合位点表现出特异性。
展开▼