POLYSACCHARIDE-PROTEIN BINDING MODEL AND NANO-FIBRIL FORMATION OF A STARCH BINDING DOMAIN

摘要

A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X₁NNNX₂X₃NYQX₄X₅X₆X₇X_8, wherein the X₁ and X₈ mean a pair of opposite charged amino acid residues, and the X₂, X₃, X₄, X₅, X₆, or X₇ means an amino acid residue is described. A mixture for diminising a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.