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FLUORESCENT PROBE FOR MEASUREMENT OF GLUCURONATE TRANSFERASE

机译:谷胱甘肽转移酶的荧光探针

摘要

A fluorescent probe for measurement of UDP-glucuronosyltransferase, which comprises a fluorescein derivative, wherein in the fluorescein derivative, the 2-carboxy group on the benzene ring of fluorescein is replaced with another monovalent substituent, provided that said substituent is a substituent other than sulfo group, and the substituent does not have carboxy group or sulfo group, and wherein the fluorescein derivative may have an arbitrary substituent at a position on the benzene ring other than the 2-position, and the fluorescein derivative may have a substituent selected from the group consisting of an alkoxy group and a halogen atom at the 2-position and/or the 7-position of fluorescein.
机译:一种用于测量UDP-葡糖醛酸糖基转移酶的荧光探针,其包含荧光素衍生物,其中在荧光素衍生物中,荧光素苯环上的2-羧基被另一个单价取代基取代,条件是所述取代基是除磺基以外的取代基。基团,并且该取代基不具有羧基或磺基,并且其中荧光素衍生物可以在苯环上除2-位以外的位置具有任意取代基,并且荧光素衍生物可以具有选自以下基团的取代基在荧光素的2-位和/或7-位由烷氧基和卤原子组成。

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