SELECTIVE DETECTION OF Hg2+ BY CALIX4ARENES

摘要

Provided herein are compounds, methods of making the compounds and methods for the sensitive and selective detection of Hg²⁺ with the compounds, which are calix[4]arenes. In particular, compounds of Formula I, wherein the variables have the values described herein, may be added to a sample to be tested for Hg²⁺. The compound of; ;Formula (I) fluoresces strongly in the absence of Hg²⁺ but is quenched upon binding of Hg²⁺ to form a complex. The decrease in fluorescence may be used to detect and quantify the amount of Hg²⁺ present in a sample. The disclosed compounds may also be used to selectively detect Hg²⁺ in samples containing other mono- or divalent metals.