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5-aryl-4,5-dihydro-(1H)-pyrazolines as cannabinoid CB1 receptor agonists
5-aryl-4,5-dihydro-(1H)-pyrazolines as cannabinoid CB1 receptor agonists
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机译:5-芳基-4,5-二氢-(1H)-吡唑啉类大麻素CB1受体激动剂
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摘要
The invention is directed to 5-(hetero)aryl-4,5-dihydro-(1H)-pyrazole (pyrazoline) derivatives as cannabinoid CB1 receptor agonists, to pharmaceutical compositions comprising these compounds, to methods for their syntheses, methods for preparing novel intermediates useful for their syntheses, and methods for preparing compositions. The invention also relates to the uses of such compounds and compositions, administered to patients to achieve a therapeutic effect in disorders in which CB1 receptors are involved, or that can be treated via manipulation of those receptors.;Compounds of the present invention include compounds of formula (I):; wherein the substituents have the definitions given in the specification.
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