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Vectors encoding cell growth and adhesion factors for simultaneous growth and adhesion of cells

机译:编码细胞生长和粘附因子以同时生长和粘附细胞的载体

摘要

The present invention relates to endothelial and smooth muscle cells genetically altered to express or over-express one or more cell adhesion factors. The invention further relates to cells genetically altered to express or over-express both cell proliferation growth factor(s) and cell adhesion factor(s). In addition, the present invention relates to nucleic acid constructs and nucleic acid construct systems that encode the cell adhesion and cell proliferation growth factors that are used to transfect/transform the cells so that they can express the factors.
机译:本发明涉及经遗传改变以表达或过表达一种或多种细胞粘附因子的内皮和平滑肌细胞。本发明进一步涉及经遗传改造以表达或过表达细胞增殖生长因子和细胞粘附因子的细胞。另外,本发明涉及编码细胞粘附和细胞增殖生长因子的核酸构建体和核酸构建体系统,所述细胞粘附和细胞增殖生长因子用于转染/转化细胞,使得它们可以表达所述因子。

著录项

  • 公开/公告号US8022195B2

    专利类型

  • 公开/公告日2011-09-20

    原文格式PDF

  • 申请/专利权人 MOSHE FLUGELMAN;

    申请/专利号US20080075657

  • 发明设计人 MOSHE FLUGELMAN;

    申请日2008-03-13

  • 分类号C07H21/04;C07H21/02;C12N15/00;A61K48/00;

  • 国家 US

  • 入库时间 2022-08-21 18:10:06

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