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Compare-MS: method rapid, sensitive and accurate detection of DNA methylation
Compare-MS: method rapid, sensitive and accurate detection of DNA methylation
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机译:Compare-MS:快速,灵敏,准确地检测DNA甲基化的方法
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摘要
The present invention provides methods and kits useful for enriching, identifying and quantifying methylated DNA3 particularly hypermethylated CpG islands by digesting a sample with a methylation-sensitive restriction endonuclease and capturing methylated restriction fragments with a methyl-binding capture reagent. The methods of the invention may be used in the detection of cancer, particularly detection of prostate cancer.
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