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Polypeptide derived from the ryanodine receptor that inhibits calcium leakage
Polypeptide derived from the ryanodine receptor that inhibits calcium leakage
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机译:源自ryanodine受体的多肽,可抑制钙泄漏
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摘要
A polypeptide exhibiting the effect of inhibiting Ca2+ leakage in a target cell, the polypeptide having the amino acid sequence of any of SEQ ID NOs: 3 to 9 or an amino acid sequence obtained through deletion, insertion, substitution, or addition of one or more amino acids in the aforementioned amino acid sequence; a polynucleotide encoding the polypeptide; and a pharmaceutical composition containing, as an active ingredient, the polypeptide or an expression product of the polynucleotide.
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机译:一种具有抑制靶细胞中Ca 2 + Sup>泄漏的作用的多肽,该多肽具有SEQ ID NO:3至9中任一个的氨基酸序列或通过缺失,插入获得的氨基酸序列在上述氨基酸序列中,一个或多个氨基酸的取代,添加或添加;编码多肽的多核苷酸;药物组合物,其含有多肽或多核苷酸的表达产物作为活性成分。
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