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Bacterial efflux pump inhibitors and methods of treating bacterial infections
Bacterial efflux pump inhibitors and methods of treating bacterial infections
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机译:细菌外排泵抑制剂和治疗细菌感染的方法
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摘要
This invention relates to the field of antimicrobial agents and more specifically it relates to Efflux Pump Inhibitor (EPI) compounds to be co-administered with antimicrobial agents for the treatment of infections caused by drug resistant pathogens. The EPI compounds are soft drugs which exhibit a reduced propensity for tissue accumulation. The invention includes novel compounds useful as efflux pump inhibitors, compositions and devices comprising such efflux pump inhibitors, and therapeutic use of such compounds.
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