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Genotyping methods using genomic sequence of the 5-lipoxygenase-activating protein (FLAP) and polymorphic markers thereof
Genotyping methods using genomic sequence of the 5-lipoxygenase-activating protein (FLAP) and polymorphic markers thereof
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机译:使用5-脂氧合酶激活蛋白(FLAP)基因组序列及其多态性标记的基因分型方法
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摘要
The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides means to determine the predisposition of individuals to diseases involving the leukotriene pathway as well as means for the diagnosis of such diseases and for the prognosis/detection of an eventual treatment response to agents acting on the leukotriene pathway.
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