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Diagnosis of abnormal blood conditions based on polymorphisms in the glycoprotein VI gene
Diagnosis of abnormal blood conditions based on polymorphisms in the glycoprotein VI gene
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机译:基于糖蛋白VI基因多态性的异常血液状况诊断
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摘要
Methods of diagnosis of abnormal blood conditions associated with an increased risk of bleeding are described. Subjects homozygous or heterozygous for the GPVIb allele are at considered to be at increased risk of bleeding. Kits for carrying out the methods of diagnosis, and use of the methods and kits for determining the GPVI allelotype of subjects in need of surgery, with a low platelet count, with an acquired bleeding disorder, on blood thinning drugs, or of blood donors is also described.
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机译:描述了与出血风险增加相关的异常血液状况的诊断方法。 GPVI b Sup>等位基因纯合或杂合的受试者被认为出血风险增加。用于执行诊断方法的试剂盒以及用于确定需要进行手术的受试者的GPVI等位基因型的方法和试剂盒的用途,这些受试者需要血小板稀少,获得性出血疾病,稀释血药或献血者也有描述。
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