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Hybrid biologic/synthetic porous extracellular matrix scaffolds

机译:混合生物/合成多孔细胞外基质支架

摘要

Methods of making a hybrid biologic/synthetic scaffold for repairing damaged or diseased tissue are provided. The methods include the step of suspending pieces of an extracellular matrix material in a liquid to form a slurry, and coating a synthetic mat with the slurry, or mixing or layering the slurry with a synthetic polymer solution. The liquid is subsequently driven off so as to form a foam. Porous implantable scaffolds fabricated by such a method are also disclosed.
机译:提供了制备用于修复受损或患病组织的生物/合成杂种支架的方法。所述方法包括以下步骤:将细胞外基质材料的碎片悬浮在液体中以形成浆料,并用所述浆料涂覆合成垫,或将所述浆料与合成聚合物溶液混合或分层。随后将液体驱除以形成泡沫。还公开了通过这种方法制造的多孔可植入支架。

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