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Method and system for predicting gene pathway using gene expression pattern data and protein interaction data

机译:利用基因表达模式数据和蛋白质相互作用数据预测基因途径的方法和系统

摘要

Provided are a method and system for predicting pathways of genes that serve the same biological purpose using gene expression pattern data and protein interaction data. The method of predicting a gene pathway includes: a first step of generating partial pathways from gene expression pattern data by using a pathway extraction algorithm, and matching the partial pathways to express them as a graph; a second step of generating partial pathways from protein interaction data by using a pathway extraction algorithm, and matching the partial pathways to express them as a graph; and a third step of combining a graph made in the first step and a graph made in the second step by using a graph matching algorithm to make a combined graph.
机译:提供了一种使用基因表达模式数据和蛋白质相互作用数据预测具有相同生物学目的的基因途径的方法和系统。预测基因途径的方法包括:第一步,通过使用途径提取算法从基因表达模式数据产生部分途径,并匹配部分途径以图表达它们。第二步,使用途径提取算法从蛋白质相互作用数据中产生部分途径,并匹配部分途径以图形方式表达它们。第三步,通过图匹配算法将第一步制作的图与第二步制作的图进行组合,得到组合图。

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