Treatment of disorders insulina.composicion resistant Pharmaceutical. Use. Kit

摘要

Claim 1: a method for treating a disorder of insulin resistance in a Mammal comprising administering to a Mammal in need an effective amount of an antagonist of il-17a and / or IL 17F.Claim 2: The Method according to claim 1, wherein the Disorder is selected from the group consisting of insulin dependent diabetes mellitus (NIDDM) ovarian hyperandrogenism, obesity, and high blood pressure. Claim 1: The Method according to claim 1, wherein the antagonist il-17a and / or IL 17F is an Antibody or its Fragments.Claim 2: The Method according to claim 5, in which the Antibody is an Antibody selected from the group consisting of anti IL - 17a, anti IL - 17F, anti IL - 17A / F and anti IL - 17RC. Claim 1: The Method according to claim 1 which comprises administering an effective amount of Addition agent for treating insulin resistance.Claim 1: The Method according to claim 10, wherein the agent to treat insulin resistance insulin, igf-1 or a sulfonylurea. Claim 1: The Method according to claim 10 also includes an effective amount of an agent capable of treating the disorder of insulin resistance.Claim 1: The Method according to claim 12, where the other Agent is Dickkopf related protein 5 (DKK) 5.