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Cho cell lines / CERT (Ceramide transfer protein)

机译:Cho细胞系/ CERT(神经酰胺转移蛋白)

摘要

The production lines of host cells comprising vector constructs comprising AN EXPRESSION cassette of CERT s132a. These cell lines have improved Growth characteristics and High expression levels of CERT s132a. In particular, two cell lines deposi In the DSMZ with Numbers acc2989 (CHO / DSM and DSM acc2990 CERT 2.20) (CHO / CERT 2.41).In addition, a method to generate such host cells and Methods of producing Preferred production of Proteins using the two cell lines deposited at the DSMZ with Numbers acc2989 (CHO / DSM and DSM acc2990 CERT 2.20) (CHO / CERT 2.41).
机译:宿主细胞的生产线包含载体构建体,所述载体构建体包含CERT s132a的表达盒。这些细胞系具有改善的生长特性和高表达水平的CERT s132a。特别是在DSMZ中存有编号为acc2989(CHO / DSM和DSM acc2990 CERT 2.20)(CHO / CERT 2.41)的两个细胞系。此外,还提供了一种生成此类宿主细胞的方法和优选产生蛋白质的方法使用存入DSMZ的编号为acc2989(CHO / DSM和DSM acc2990 CERT 2.20)(CHO / CERT 2.41)的两条细胞系。

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