immunogenic composition, vaccine kit, vaccine, process for making the vaccine, method for immunizing a human host against disease caused by infection, use of the immunogenic composition or vaccine, and methods for eliciting a protective immune response in infants against otitis media and against s. pneumonia and to elicit a protective immune response in the elderly against s. pneumonia

摘要

IMMUNOGENIC COMPOSITION, VACCINE KIT, VACCINE, PROCEDURE FOR MAKING VACCINE, METHOD FOR IMMUNIZING A HUMAN HOSPITAL AGAINST DISEASE CAUSED BY INFECTION, USE OF IMMUNOGENIC COMPOSITION OR VACCINE METHOD FOR RESPONSE S. PNEUMONIA AND TO ELICIT AN ELDERLY PROTECTIVE IMMUNE RESPONSE AGAINST S. PNEUMONIA The present invention is in the field of capsular saccharide conjugate pneumococcal vaccines. Specifically, a multivalent immunogenic composition of Streptococcus pneumoniae is provided with several conjugated capsular saccharides of different 5 pneumoniae serotypes conjugated to 2 or more different carrier proteins, wherein the composition comprises diphtheria toxoid (DT) conjugated serotype 1 9F capsular saccharide. or CRM 197, optionally wherein 19F is the only saccharide in the diphtheria toxoid (DT) conjugated composition or CRM197.