Specific amplification of fetal DNA sequence of a mixture of fetal origin - maternal.

摘要

b amplification specific for fetal DNA sequence of a mixture of fetal origin - maternal d . The present invention provides a method of amplifying sejetivamente fetal DNA sequences from a mixture of foetal origin - maternal.This method uses differential methylation to allow selective amplification of specific sequ00fau00eancias / foetal trophoblast from mixtures of DNA that contain a high proportion of non trofoblu00e1stico / fetal DNA. The invention also provides methods for the use of DNA sequences amplified for detection of fetal aneuploidy.