Hypoglycemic effect of fruit - wolf (Solanum lycocarpum st.hil.)

摘要

Hypoglycemic effect of fruit - wolf (Solanum iycocarpum St. hili). The present invention seeks to obtain the powder of fruit - of - the - wolf (solanumiycocarpum St. HIL) and evaluate its hypoglycemic effect. The powder of the fruit of the wolf is a phytotherapeutic product extracted from the pulp of the fruit - of - the - Wolf green and popularly used.The selected fruit were washed, peeled and chopped, the seeds removed, ground and the powder obtained was filtered, purified, washed with distilled water twice and dried in the oven, forced ventilation. The sample was crushed into and stored. In the evaluation of the blood glucose lowering effect was twenty four adult rats, male, Wistar strain.Sixteen of these were subjected to induction of diabetes with streptozotocin. The animals were divided into normal control, diabetic and diabetic treated control. The blood glucose was assessed weekly, in addition to the parameters: weight, food intake and water intake, urine. Histologias blades were made at the end of the experiment to verify the lesions in the liver and pancreas.The powder of the fruit of the wolf reduces glycaemia in about 15 to 25% in diabetic treated rats, showing that essefitoteru00e1pu00edco is as effective as lowering activity in rats. In diuresis there was a significant difference between the groups in diabetics and non diabetics.Animals of the control group normal evolved within the normal range during the experiment in relation to diuresis and water intake. In anu00e1bse histology of liver and pancreas, it is concluded that there was no difference in relation to the optical microscopy.