Compositions comprising a Plurality of particles, each of which comprises a Digestive Enzyme that contains a Core coated with an Enteric Polymer and at least one alkylating Agent

摘要

1 - Una composici n que comprende por lo menos una enzima digestiva en donde la composici n tiene un contenido de humedad de aproximadamente 3 25 o menos 2 - La composici n de la reivindicaci n 1 en donde el contenido de humedad es aproximadamente 2 25 o Genes, formamide, cells, carboxamide, and their mixtures. 4. The ingredient required in Item 3, wherein at least one digestive enzyme is a fat. 5. Ingredients required in Item 3, at least one digestive enzyme is insulin. 6. - ingredients required in Item 4, including animal fat, bacterial fat, fungal fat, vegetable fat, compound fat, synthetic fat, chemically modified fat or mixture thereof. 7. The composition of claim 1, including at least one acceptable pre patent holder for the drug. 8. composition of the seventh requirementIn this case, at least one pharmaceutically acceptable precursor chemical is selected from polymers, splitters, lubricants, gliders, diluents and mixtures. 9. The composition of claim 7, wherein at least one pharmaceutically acceptable precursor is a stabilizer selected from the following substances: trihalogens, prolina, dextrano, maltosa, sucrose, manitol, POLYOLE, silica gel, aminomycin, pyridan and their mixture. 10. Composition of claim 7At least one pharmaceutically acceptable precursor chemical is a polymer selected from the group, including starch, sugar, lactose, glycol, one glycol, sorbitol, maltol, cellulose, microcrystalline cellulose, modified cellulose, hydroxypropyl cellulose, sodium carbonate cellulose, Aleconic acid, PVC.