DERIVATIVES OF 3,5-DIAMINO-6-CHLORPYRAZIN-2-CARBIC ACID AND THEIR APPLICATION AS EPITELIAL SODIUM CHANNEL BLOCATORS FOR THE TREATMENT OF RESPIRATIVE DISEASES

摘要

The application describes a compound of formula I in free form or in the form of a salt or solvate in which R, R, R, R, R, R, R, R and R have the meanings specified in the description, applicable for the treatment of diseases that respond to blocking of epithelial sodium channels. The application also describes pharmaceutical compositions that contain these compounds, and methods for producing these compounds.