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IMIDAZOPIRIDINE DERIVATIVES AS AN INHIBITOR ACTIVATIVE-LIKE RECEPTOR KINASE (ALK-4 OR ALK-5)

机译:咪唑并吡啶衍生物作为抑制剂活性受体激酶(ALK-4或ALK-5)

摘要

The application describes the compounds of formula I in free form or in the form of a salt or solvate, in which X, R, R, R and R have the meanings indicated in the description, which are applicable for the treatment of diseases mediated by the ALK-5 and / or ALK-4 receptor. The application also describes pharmaceutical compositions that contain these compounds, and methods for producing these compounds.
机译:本申请描述了游离形式或盐或溶剂化物形式的式I化合物,其中X,R,R,R 1和R 2具有说明书中所指示的含义,其适用于治疗由以下药物介导的疾病: ALK-5和/或ALK-4受体。该申请还描述了包含这些化合物的药物组合物,以及制备这些化合物的方法。

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