FUSED BICYCLIC CARBOXAMIDE DERIVATIVES AND USES THEREOF IN THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT OR PROPHYLAXIS OF CHEMOKINE MEDIATED DISEASES AND OF ACUTE AND CHRONIC INFLAMMATORY DISEASES

摘要

The invention relates to compounds of the formula (I) in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases such as inflammatory diseases.