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SEPARATION METHOD OF BIOLOGICAL OBJECTS RELATIVE TO THEIR VISCOELASTIC PROPERTIES

机译:与其粘弹性特性相关的生物对象的分离方法

摘要

The present invention relates to a method for the separation of biological objects in a solution which have different viscoelastic properties, wherein said method comprises a filtration step allowing the higher viscoelastic biological objects to pass through the membrane while retaining the lower viscoelastic biological objects above the membrane, and a recovery step wherein the separated lower viscoelastic biological objects are recovered above or onto the membrane and/or the separated higher viscoelastic biological objects are recovered in the filtrate. Advantageously, the biological objects are cells. More advantageously, the recovered cells are viable cells. In one preferred embodiment, the cells are tumor cells. In another preferred embodiment, the cells are fetal cells and the method finds an application in prenatal diagnosis.
机译:本发明涉及一种用于在具有不同粘弹性的溶液中分离生物物体的方法,其中所述方法包括过滤步骤,其允许较高的粘弹性生物物体通过膜,同时将较低的粘弹性生物物体保持在膜上方。以及回收步骤,其中将分离出的较低粘弹性生物物体回收到膜上方或上方,和/或将分离出的较高粘弹性生物物体回收到滤液中。有利地,生物物体是细胞。更有利地,回收的细胞是活细胞。在一优选实施方案中,细胞是肿瘤细胞。在另一个优选的实施方案中,细胞是胎儿细胞,并且该方法在产前诊断中找到了应用。

著录项

  • 公开/公告号IL202829D0

    专利类型

  • 公开/公告日2011-08-01

    原文格式PDF

  • 申请/专利权人 HERA DIAGNOSTICS;CANOPUS BIOSCIENCE LTD;

    申请/专利号IL20090202829

  • 发明设计人

    申请日2009-12-17

  • 分类号C12Nnull/null;

  • 国家 IL

  • 入库时间 2022-08-21 18:06:19

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