A METHOD FOR ENHANCING THERAPEUTIC QUALITIES AND INCREASING THERAPEUTIC INDEX OF THE DRUGS

摘要

The present invention relates to a method for enhancing the therapeutic qualities of a drug like improved taste or smell; desired octanol / water partition coefficient; improved stability; enhanced penetration of blood-brain barrier; elimination of first pass effect in the liver; reduction of enterohepatic recirculation; painless injection with parental formulation; improved bioavailability; improved changes in the rate of absorption; reduced side effects; dose proportionality; selective hydrolysis of the derivative at site of action; controlled release properties; targeted drug delivery; reduction in toxicity; reduced dose; alteration of metabolic pathway to deliver more drug at the site of action; increased solubility in aqueous solution; enhanced efficacy and increasing therapeutic index of the drug.