Method of examining immune function, method for selecting cancer patient, method of predicting cancer therapeutic effect, agent for increasing intracellular calcium ion concentration, selective function improving agent of effector memory (EM) and effector (EFF) in tumor tissue, and monitoring method of the effect of therapeutic drug for cancer

摘要

In the present invention, peripheral blood of a human subject is collected, and after applying an immunostimulant, the transition of calcium ion concentration in peripheral blood mononuclear cells (PBMC) or CD8 T cells is examined. When the calcium ion concentration in PBMC or CD8 T cells increases and then returns to the pre-stimulation state, it is judged that systemic immune function is decreased, and calcium in PBMC or CD8 T cells is applied after application of the immunostimulant. The present invention relates to a method for examining immune function, in which the immune function of the whole body is judged to be normal when the ion concentration is in an increasing trend.