ELECTROCHEMICAL DETECTION USING SILVER NANOPARTICLE LABELLED ANTIBODIES

摘要

A method for determining the presence or amount of a metal-labelled analyte (12) in a sample is described. The method comprises the steps of adding a release agent (20) to the metal labelled analyte (12) to release the metal label (18) from the analyte (12), the release agent (20) forming a charged stable species (22) with the metal label (18), applying a potential to bring the charged stable species (22) to an electrode (22), dissolving the charged stable species (22) under a positive potential to form metal ions (26), and carrying out a quantitative determination procedure such as anodic stripping voltammetry to determine the presence or amount of the metal-labelled analyte (12).