DEVICE FOR THE CONTINUOUS RECOVERY OF BIOPARTICLES BY MEANS OF AQUEOUS TWO-PHASE SYSTEMS AND OPERATION METHOD THEREOF.

摘要

The present invention refers to a device for the continuous recovery of bioparticles by means of aqueous two-phase systems and method for the operation thereof, which is performed at intervals or in a continuous manner, where the partition, separation and/or recovery of proteins and biological and non-biological compounds, of food, pharmaceutical or industrial interest were related by means of aqueous two-phase systems in continuous systems. The device is characterised in that, besides the whole benefits provided by the aqueous two-phase systems in the primary recovery of biocompounds, the system promotes a continuous flow. The invention does not require a disperse phase and a continuous phase, and has no overflow problems, since the speeds may be easily modified. The construction of the invention is ergonomic, thus using the same volume amount in a reduced space. The system does not change with regard to the type of polymer or salts used, thus being more selective and allowing the re ticulation of the phases to be performed within the device. The present invention avoids unitary operation such as centrifugation, agitation and decantation, which allows bioparticles to be recovered in a manner more efficient than the current aqueous two-phase systems, which perform each unitary operation in independent devices and equipments, the invention also facilitating the recovery of each of the phases of the aqueous two-phase systems, saving power and reducing the operation time.