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ANTI-CD8 ANTIBODIES BLOCK PRIMING OF CYTOTOXIC EFFECTORS AND LEAD TO GENERATION OF REGULATORY CD8+T CELLS.
ANTI-CD8 ANTIBODIES BLOCK PRIMING OF CYTOTOXIC EFFECTORS AND LEAD TO GENERATION OF REGULATORY CD8+T CELLS.
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机译:细胞毒性因子的抗CD8抗体启动和导致调节性CD8 + T细胞的产生。
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摘要
The present invention includes compositions and methods for inducing tolerance in a subject in need thereof comprising providing the subject with an effective amount of an anti-CD8 antibody sufficient in induce CD8sup+/sup T cell immune tolerance to allogeneic antigens.
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机译:本发明包括用于在有需要的受试者中诱导耐受的组合物和方法,包括向受试者提供足以诱导对同种异体抗原的CD8 s + T细胞免疫耐受的有效量的抗CD8抗体。
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