FORMULATION FOR DELIVERING LIPID-LOWERING DRUGS BY ORAL TRANSMUCOSAL ADMINISTRATION.

摘要

The invention relates to a formulation for delivering at least one lipid-lowering active principle by oral transmucosal administration, preferably of the statin family, said formulation including said active principle in the form of a base or a salt, a hydroalcoholic solution containing water and ethanol with an alcoholic content of at least 30% ABW, and optionally a pH correcting agent and/or an anti-oxidiser, said active principle being at a stable and complete dissolution state in the hydroalcoholic solution. The invention also relates to a method for preparing said formulation and to the use thereof, preferably in a single-dose packaging, for treating and preventing hyperlipemia and/or cardiovascular disorders.