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USE OF ESTRADIOL VALERATE OR ESTRADIOL COMBINED WITH DIENOGEST FOR THE ORAL THERAPY OF DYSFUNCTIONAL UTERINE BLEEDING IN THE FORM OF ORAL CONTRACEPTIVES
USE OF ESTRADIOL VALERATE OR ESTRADIOL COMBINED WITH DIENOGEST FOR THE ORAL THERAPY OF DYSFUNCTIONAL UTERINE BLEEDING IN THE FORM OF ORAL CONTRACEPTIVES
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机译:缬草酸雌二醇或雌二醇与狄诺吉司合用以口服避孕药形式治疗功能障碍性子宫出血的口服治疗
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摘要
Use of estradiol valerate with 17alpha -cyanomethyl-17-beta -hydroxyestra-4,9-diene-3-one for producing a multi-phase combination preparation for the oral therapy of the dysfunctional uterine bleeding in the form of oral contraceptives. The combination of estradiol valerate with dienogest comprises a first phase consisting of 2 daily dose units of estradiol valerate, a second phase consisting of 2 groups of daily dose units of the combination, where the first group contains 5 daily dose units and the second group contains 17 daily dose, and a third phase consisting of 2 daily dose units. Use of estradiol valerate with 17alpha -cyanomethyl-17-beta -hydroxyestra-4,9-diene-3-one (dienogest) for producing a multi-phase combination preparation for the oral therapy of the dysfunctional uterine bleeding, in the form of oral contraceptives. The combination of estradiol valerate with dienogest comprises a first phase consisting of 2 daily dose units of estradiol valerate at 3 mg, a second phase consisting of 2 groups of daily dose units, where the first group contains 5 daily dose units of a combination of 2 mg estradiol valerate and 2 mg of dienogest and the second group contains 17 daily dose units consisting of a combination of 2 mg of estradiol valerate and 3 mg of dienogest, a third phase consisting of 2 daily dose units having 1 mg of estradiol valerate and an additional phase consisting of 2 daily dose units on a pharmaceutically harmless placebo. The entire daily dose units of the multi-phase combination corresponds to 28 days. ACTIVITY : Contraceptive; Gynecological. MECHANISM OF ACTION : None given.
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