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SILYL-PROTECTED HYDROXYMETHYL-CARBAMOYL ALKYL KETONE AS INTERMEDIATE IN THE PREPARATION OF DOPAMINE BETA HYDROXYLASE INHIBITORS
SILYL-PROTECTED HYDROXYMETHYL-CARBAMOYL ALKYL KETONE AS INTERMEDIATE IN THE PREPARATION OF DOPAMINE BETA HYDROXYLASE INHIBITORS
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机译:甲硅烷基羟甲基-氨基甲酰基烷基酮作为多巴胺β-羟化酶抑制剂的中间体
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摘要
Compounds of formula I EMI ID=1.1 HE=45 WI=59 LX=792 LY=792 TI=CF PCwhere R Ü , R Þ and R ý are various optional substituents, R Ú is H, alkyl or alkylaryl, X is CH Þ , O or S, and n is 1, 2 or 3, with the proviso that if X is CH Þ , n is not 1, have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure. Intermediates in their preparation are also novel compounds.
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