首页> 外国专利> SPECIFIC HUMAN MONOCLONAL ANTIBODY FOR LIPOPOLISACARIDS (LPS) OF SEROTYPE IATS 011 OF PSEUDOMONAS AERUGINOSA.

SPECIFIC HUMAN MONOCLONAL ANTIBODY FOR LIPOPOLISACARIDS (LPS) OF SEROTYPE IATS 011 OF PSEUDOMONAS AERUGINOSA.

机译:绿脓杆菌血清型011的脂多糖(LPS)的特定人类单克隆抗体。

摘要

Human monoclonal antibody specific for lipopolysaccharide (LPS) of serotype IATS 011 of P. aeruginosa comprising a light chain and a heavy chain where the variable region of the light chain has the amino acid sequence of SEQ ID NO: 7 and the region The heavy chain variable has the amino acid sequence of SEQ ID NO: 8, or a mutein of said antibody capable of binding to said LPS, wherein the amino acid sequence of the variable region of the antibody light chain is at least the 95% homologous to SEQ ID NO: 7 and the amino acid sequence of the variable region of the antibody heavy chain is at least 95% homologous to SEQ ID NO: 8.
机译:对铜绿假单胞菌血清型IATS 011的脂多糖(LPS)具有特异性的人单克隆抗体,包含轻链和重链,其中轻链的可变区具有SEQ ID NO:7的氨基酸序列,而重链区域可变区具有SEQ ID NO:8的氨基酸序列,或所述抗体能够与所述LPS结合的突变蛋白,其中抗体轻链可变区的氨基酸序列与SEQ ID NO:1至少95%同源。 NO:7和抗体重链可变区的氨基酸序列与SEQ ID NO:8至少95%同源。

著录项

  • 公开/公告号ES2348263T3

    专利类型

  • 公开/公告日2010-12-02

    原文格式PDF

  • 申请/专利权人 KENTA BIOTECH AG;

    申请/专利号ES20060706900T

  • 申请日2006-02-13

  • 分类号C07K16/12;A61K31/7088;A61K39/40;A61P31/04;C12N5/10;C12N15/12;C12N15/13;C12N15/79;C12Q1/68;G01N33/569;G01N33/577;

  • 国家 ES

  • 入库时间 2022-08-21 18:02:50

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