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TIENOPIRIDINES AS ALLOSTERIC POTENTIALS OF THE M4 MUSCARINIC RECEIVER.
TIENOPIRIDINES AS ALLOSTERIC POTENTIALS OF THE M4 MUSCARINIC RECEIVER.
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机译:替尼派定是M4肌肉受体的变构电位。
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摘要
A compound of Formula I: ** (See formula) ** m is 1 or 2; n is 0, 1 or 2; X is a bond, -O-, -SOp-, -C (O) -, -NR2-, -C (O) -NR2-or -NR2-C (O) -; p is 0, 1 or 2; R1 is hydrogen, hydroxyl, C1-C4 alkyl, phenyl, pyridyl, pyrrolidinyl, piperazinyl, morpholino, thiazolyl, imidazolyl or 1,3-dioxalanyl; whose phenyl, piperazinyl or thiazolyl group may be optionally substituted with a substituent selected from the group consisting of halo or C1-C2 alkyl; where n cannot be 0 when p is 0, or when X is -O-, -NR2 or -NR2-C (O) -; R2 is hydrogen or C1-C2 alkyl; whose C1-C2 alkyl may be optionally substituted with a hydroxyl; or a pharmaceutically acceptable salt thereof.
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