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Oxytocin for use in the treatment of autism and Asperger's disorder.

机译:催产素用于治疗自闭症和阿斯伯格症。

摘要

Composition comprising oxytocin, oxytocin analog selected from the group consisting of 4-threonine-1-hydroxy-desaminooxitocina, 9-desamido-oxytocin, 7-D-proline-oxytocin and its deamino analog, (2,4- diisoleucina) -oxytocin, desamino-oxytocin analogue 1-deamino-1- monocarba-E12- [Tyr (OMe)] - OT (dCOMOT), carbetocin, Ile-conopresina, atosiban, [Thr4-Gly7] - oxytocin, oxipresina, desamino-6-carba-oxytocin (DC60), d [Lys (8) (5 / 6C-Flu)] VT, d [Thr (4), Lys (8) (5 / 6C-Flu)] VT, [HO (1)] [Lys (8) (5 / 6C-Flu)] VT, [HO (1)] [Thr (4), Lys (8) (5 / 6C-Flu)] VT, d [Orn (8 ) (5 / 6C-Flu)] VT, d [Thr (4), Orn (8) (5 / 6C-Flu)] VT, [HO (1)] [Orn (8) (5 / 6C-Flu) ] VT and [HO (1)] [Thr (4), Orn (8) (5 / 6C-Flu)] VT or combination thereof for use in treating autism or Asperger's disorder.
机译:组合物包含催产素,催产素类似物,所述催产素类似物选自4-苏氨酸-1-羟基-脱氨基催产素,9-脱酰胺基催产素,7-D-脯氨酸催产素及其脱氨基类似物,(2,4-二异亮氨酸)-催产素去氨基催产素类似物1-deamino-1-monocarba-E12- [Tyr(OMe)]-OT(dCOMOT),卡贝托星,Ile-conopresina,阿托西班,[Thr4-Gly7]-催产素,oxipresina,desamino-6-carba-催产素(DC60),d [Lys(8)(5 / 6C-Flu)] VT,d [Thr(4),Lys(8)(5 / 6C-Flu)] VT,[HO(1)] [Lys (8)(5 / 6C-Flu)] VT,[HO(1)] [Thr(4),Lys(8)(5 / 6C-Flu)] VT,d [Orn(8)(5 / 6C- Flu)] VT,d [Thr(4),Orn(8)(5 / 6C-Flu)] VT,[HO(1)] [Orn(8)(5 / 6C-Flu)] VT和[HO( 1)] [Thr(4),Orn(8)(5 / 6C-Flu)] VT或其组合,用于治疗自闭症或阿斯伯格症。

著录项

  • 公开/公告号ES2353690T3

    专利类型

  • 公开/公告日2011-03-04

    原文格式PDF

  • 申请/专利权人 NEUROPHARMACOLOGY SERVICES LLC;

    申请/专利号ES20030770645T

  • 发明设计人 HOLLANDER ERIC;

    申请日2003-10-03

  • 分类号A61K38/00;A61Bnull/null;A61K38/095;A61P25/00;

  • 国家 ES

  • 入库时间 2022-08-21 18:02:45

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