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humanized antibody specific for the factor-alpha tumor necrosis of.

机译:特异性针对因子-α肿瘤坏死的人源化抗体。

摘要

A humanized antibody specific for the factor α tumor necrosis-human (hTNF-α) comprising: a) a variable region of the heavy chain having the amino acid sequence of SEQ ID NO: 36, 37 or 38; b) a variable region of the light chain having the amino acid sequence of SEQ ID NO: 39 or 40; c) a constant region of the heavy chain identical to that of a human antibody; d) a constant region of the light chain identical to a human antibody.
机译:对人因子α肿瘤坏死因子(hTNF-α)具有特异性的人源化抗体,其包括:a)具有SEQ ID NO:36、37或38的氨基酸序列的重链的可变区;和b)具有氨基酸序列SEQ ID NO:39或40的轻链的可变区; c)与人抗体相同的重链恒定区; d)与人抗体相同的轻链恒定区。

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