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Arilanilina derivatives as beta2 adrenergic receptor agonists.

机译:Arilanilina衍生物作为β2肾上腺素能受体激动剂。

摘要

Compound of formula (II): ** (See formula) ** wherein R1 and R2 taken together are -NHC they (= O) CH = CH-; and R5 is selected from -O-C1-6alquilenilo-NR10R11 and NR12R13 C1-6alquilenilo-and R6 is hydrogen, or R5 is C 1-4 alkoxy and R6 is-C1-6alquilenilo-NR12R13 where each of R10, R11, R13 R12y is independently hydrogen or C1-4 alkyl or R10 and R11 together with the nitrogen atom to which they are attached form a piperazinyl ring, or a salt or solvate or stereoisomer thereof.
机译:式(II)的化合物:**(参见式)**其中R 1和R 2一起为-NHC,它们(= O)CH = CH-;并且R5选自-O-C1-6alquilenilo-NR10R11和NR12R13 C1-6alquilenilo-并且R5是氢,或者R5是C 1-4烷氧基并且R6是-C1-6alquilenilo-NR12R13,其中R10,R11,R13,R12y是R 5是氢或C 1-4烷基或R 10和R 11与它们所连接的氮原子一起形成哌嗪基环,或其盐或溶剂合物或立体异构体。

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