An IPV vaccine comprising: (a) diphtheria toxoid; (B) tetanus toxoid; (C) killed whole cells of Bordetella pertussis; or two or more acellular pertussis components (Pa) (e.g. pertussis toxoid (PT), filamentous haemagglutinin (FHA) and pertactin (PRN)), and (d) poliovirus type 1 inactivated in a higher dose 10 antigen units D and less than 20 D-antigen units, wherein the vaccine is substantially thiomersal free.
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