首页> 外国专利> COMBINATION OF AMINO ACIDS, ACYLCARNITINES AND BIOGENIC AMINES FOR THE ASSESSMENT OF CHRONIC KIDNEY DISEASE

COMBINATION OF AMINO ACIDS, ACYLCARNITINES AND BIOGENIC AMINES FOR THE ASSESSMENT OF CHRONIC KIDNEY DISEASE

机译:氨基酸,酰基烟碱和生物胺的联合用于评估慢性肾脏病

摘要

The present invention relates to a metabolic biomarker set for assessingkidney disease comprising at least twoamino acids, at least two acylcarnitines and at least two biogenic amines.Moreover, the present invention relates to a method forassessing kidney disease in a mammalian subject which comprises obtaining abiological sample, preferably blood and /or urine,from the subject and measuring in the biological sample the amount of at leasttwo amino acids, of at least two acylcarnitines andof at least two biogenic amines, as well as to a kit adapted to carry out themethod. By employing the specific biomarkers and themethod according to the present invention it becomes possible to more properlyand reliably assess kidney disease.
机译:本发明涉及用于评估的代谢生物标志物组肾脏疾病,包括至少两种氨基酸,至少两种酰基肉碱和至少两种生物胺。而且,本发明涉及一种用于评估哺乳动物受试者的肾脏疾病,包括获得生物样品,最好是血液和/或尿液,并从生物样本中测量至少至少两个酰基肉碱中的两个氨基酸和至少两种生物胺,以及适用于进行方法。通过使用特定的生物标志物和根据本发明的方法,可以更适当地进行并可靠地评估肾脏疾病。

著录项

  • 公开/公告号CA2763948A1

    专利类型

  • 公开/公告日2010-12-09

    原文格式PDF

  • 申请/专利权人 BIOCRATES LIFE SCIENCES AG;

    申请/专利号CA20092763948

  • 发明设计人 LUNDIN ULRIKA;WEINBERGER KLAUS;

    申请日2009-06-02

  • 分类号G01N33/48;G01N33/487;

  • 国家 CA

  • 入库时间 2022-08-21 18:01:59

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